Liliya Vugmeyster, Ph.D
Abstract
NMR spectroscopy has evolved as a versatile tool in investigations of properties of different materials, and biomolecules. The field also provides opportunities for theoretical and technological developments of the techniques. Using selected studies from my research group, I will demonstrate multiple applications of NMR relaxation in investigations of dynamics of biomolecules and materials. These studies are conducted in either solution or solid phases to suit the properties of the systems. For example, amyloid-b aggregates, involved in Alzheimer’s Disease, are not very soluble and often require working under solid phase conditions. Additionally, I will demonstrate the power of NMR of quadrupolar nuclei, such as 17O, 2H, and 59Co, in investigations of molecular dynamics. Lastly, sophisticated simulations tools are needed to relate the spectroscopic observables to the mechanisms and time scales of molecular motions, and we will discuss some of these approaches used in the lab.
When: February 6, 2025
Where: North Classroom
Time: 11:00 am - 12:00pm