March 14, 2025 -Seminar-Dopamine Beyond the Classical Pathways

Published: March 10, 2025

Aaron K. Apawu, PhD

Abstract

Neurotransmitters are chemical messengers that play a crucial role in neuronal communication. Specifically, dopamine has been implicated in movement, learning, memory, emotions, reward related behaviors and several neurological disorders, including addiction, Schizophrenia, and Parkinson’s disease. However, it is becoming increasingly apparent that dopamine’s role goes beyond the classical pathways. For example, the significant presence of dopamine in the central auditory system connects the monoamine neurotransmitter to auditory functions. In this seminar, I will discuss how the superior temporal resolution of analytical chemistry technique like fast scan cyclic voltammetry together with complementary tools have been used to explore dopaminergic inputs in the central auditory system and their dysfunction following acoustic trauma. I will also discuss possible mechanisms behind these dysregulations and their implications. Overall, the findings from my lab provide important insight into the neurochemical bases for noise-induced deafness and its related disorders.

When: March 14, 2025

Where: North Classroom 1535

Time: 11:00 am - 12:00pmc