Scott Horowitz PhD

Abstract

The complexity of protein folding and unfolding in the cell is staggering, and is affected by many factors. A major factor is the role of RNA as both a chaperone and aggregation-inducer. In this seminar, I will discuss our investigations into which RNAs are important, what they are doing with regards to both protein folding and misfolding, and how this impacts neurodegenerative disease and aging. We will conclude by discussing our work incorporating structural biology data and educational tools into the biochemistry citizen science video game Foldit.
 

When: March 29, 2024

Where: North Classroom 1130

Time: 11:00 am - 12:00 pm