Phiel Lab (highlighted for teaching) discovers new facet of stem cell biology

Published: Sept. 6, 2018

New research from Integrative Biology Associate Professor Christopher Phiel (and colleges) Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells describes an intersection between these components in the regulation of m6 A by GSK-3. The research found that that protein levels for the RNA demethylase, FTO (fat mass and obesity– associated protein), are elevated in Gsk-3;Gsk-3-deficient mouse embryonic stem cells (ESCs) F. In addition, Phiel’s lab was recently highlighted in The CRISPR Journal (Issue 1, volume 2) for its excellence in undergraduate education, student-centered practices, and student-focused research opportunities resulting in enhanced biology education and comprehension.