Leo Bruederle photo

Leo P. Bruederle

Ph.D. • Professor Emeritus
Department of Integrative Biology
Expertise Areas: Dr. Bruederle's research interests include the evolution of species rich genera such as Carex (Cyperaceae), which comprises approximately 2000 species worldwide. He is interested specifically in the evolutionary mechanisms that facilitate speciation in this large genus. Additional interests include: plant systematics at and below the level of genus, population genetics and endemism, conservation genetics, and biogeography. He is also interested in the implementation, institutionalization, and assessment of undergraduate research.
leo.bruederle@ucdenver.edu     303.315.7677
Amanda Charlesworth photo

Amanda Charlesworth

Ph.D. • Associate Professor • Assistant Chair
Department of Integrative Biology
Expertise Areas: Molecular developmental biology. Regulation of gene expression by RNA translational control and its role in cell cycle progression during oocyte maturation, maternal to embryo transition, and early development.
Greg Cronin photo

Greg Cronin

Ph.D. • Associate Professor
Department of Integrative Biology
Expertise Areas: Dr. Cronin uses a transdisciplinary approach to restore and protect ecosystems. He is a fan of using the STEAM disciplines (Science, Technology, Engineering, Arts, and Math) to promote a sustainable society and protection of Earth’s ecosystems. Two main foci of this scholarship are using aquaponics to sustainably produce food and restoring watersheds in Haiti.
gregory.cronin@ucdenver.edu     303.315.7647
Charles Ferguson photo

Charles A. Ferguson

Ph.D. • Professor • Director, Health Professions Advising
Department of Integrative Biology
Expertise Areas: First year Experience/Success of STEM students and Health Professions Advising Education & Degrees PhD., Neuroscience, University of Colorado, Boulder, 1996 M.A., Neurophysiology, University of Colorado, Denver, 1987 B.A., Biology, University of Colorado, Denver, 1985 Bio Dr. Ferguson has been on the faculty at the University of Colorado Denver since 1985 and teaches in the Dept. of Integrative Biology. He has been nationally recognized for excellence in teaching and...
charles.ferguson@ucdenver.edu     303.315.7535
Michael Greene Photo

Michael J. Greene

Ph.D. • Associate Professor
Department of Integrative Biology
Expertise Areas: Chemical Ecology, Behavioral Ecology
michael.greene@ucdenver.edu     303.315.7672
Laurel Hartley photo

Laurel Hartley

Ph.D. • Associate Professor
Department of Integrative Biology
Expertise Areas: My science education research interests are concerned with assessing and improving how students understand biological concepts and apply scientific principles, especially concepts and principles related to ecology. I work at both the undergraduate and grades 6-12 levels. My approach to this research employs both quantitative and qualitative data collection and analysis methods. I enjoy working on large-scale, multi-faceted collaborative projects that seek to answer transformative and often complicated research questions. Thus, some of the projects I work on involve many collaborators from across the country. My goals as a science education researcher are to make discoveries that can be used for improving pedagogy and assessment in undergraduate biology education and for informing the development of national science standards and practices for K-12 education. My ecological research bridges community and ecosystem ecology to explore how plant communities and soils respond to external factors such as intensive herbivory, nutrient inputs, emerging infectious diseases, and climate change. The model system that I work on has shaped and integrated the questions that I pursue. I study the impact of introduced bubonic plague on both urban and rural black-tailed prairie dog (Cynomys ludovicianus) communities. My field research involves mostly observational studies across space and time gradients. I conduct greenhouse experiments to further explore the mechanisms underlying the broad patterns I observe in the field. Much of my research is situated in and around urban Denver, making it easily accessible to UC Denver student researchers.
laurel.hartley@ucdenver.edu     303.315.7667
Christopher Miller photo

Christopher S. Miller

Ph.D. • Assistant Professor
Department of Integrative Biology
Expertise Areas: The Miller lab develops and uses bioinformatic and genome-enabled approaches to study microbial communities. With the advent of new sequencing technologies, one can sequence billions or trillions of base pairs of DNA for relatively little money. One of the most powerful applications of this new economy is the direct sequencing of microbial DNA and RNA from the environment. The combination of deep sequencing and bioinformatics reveals that even “simple” natural microbial communities are in fact quite complex. The Miller lab is interested in understanding this complexity at a systems level for microbial communities relevant to the environment, bioenergy production, and human health and disease.
chris.miller@ucdenver.edu     303.315.7665
Annika Mosier photo

Annika C. Mosier

Ph.D. • Assistant Professor
Department of Integrative Biology
Expertise Areas: Environmental Microbiology
annika.mosier@ucdenver.edu     303.315.7657
Christopher Phiel photo

Christopher J. Phiel

Ph.D. • Associate Professor
Department of Integrative Biology
Expertise Areas: The main interests in our lab revolve around understanding the functions of the enzyme glycogen synthase kinase-3 (Gsk-3) isoforms. We are utilizing a systems biology approach to understanding Gsk-3 function in maintaining pluripotency of embryonic stem cells. We have recently identified a role for Gsk-3 in regulating the methylation of mRNA. This modification, referred to as m6A, affects many aspects of RNA biology, including regulating the stability of mRNA and the translational efficiency. We are currently investigating the mechanisms underlying these effects, and their implications on the biology of stem cells.
christopher.phiel@ucdenver.edu     303.315.7678
Greg Ragland photo

Greg Ragland

Ph.D. • Assistant Professor
Department of Integrative Biology
Expertise Areas: The Ragland Lab is interested in the process of local adaptation to changing environments, and the mechanisms underlying animal hibernation. Our goal is to understand the mechanisms and targets of natural selection, integrating studies from genomes, to physiology, to whole organism performance. Please refer to the lab website for more information: https://seasonaladaptation.org
gregory.ragland@ucdenver.edu     303.315.7673
Timberley Roane photo

Timberley Roane

Ph.D. • Associate Professor & Director of ESIL Certificate
Department of Integrative Biology
Expertise Areas: Microbiology; microbial ecology; microbial physiology; chemical detoxification; remediation; human microbiome; see Roanemicrobiology.weebly.com for more information. As a member of the Lumbee Tribe of North Carolina, I mentor Indigenous students and am the faculty sponsor for the CU Denver AISES student group (AISES: American Indian Science and Engineering Society)
timberley.roane@ucdenver.edu     303.315.7654
Brad Stith photo

Brad Stith

Ph.D. • Professor
Department of Integrative Biology
Expertise Areas: Studying how lipids regulate fertilization, we have recently discovered a new step in fertilization, and a possible new pathway to cancer. Using sperm and eggs from Xenopus laevis, we conduct in vitro fertilization to study the biochemical and biophysical steps of how the sperm and egg fuse their membranes, activate phospholipase D1b to produce phosphatidic acid (PA) which binds and activates Src tyrosine kinase. We also study how phospholipase C isoforms are activated by Src and lipids like PA. Finally, we study how IP3 is produced and how it releases intracellular calcium at fertilization. Through a calcium sensitive dye, we record an increase in intracellular calcium first at the sperm-egg binding site, and a wave is then generated to travel across the zygote. We use HPLC and Mass spec separation with evaporative light scattering detection for lipid analysis, and phosphospecific western analysis with our dual laser Odyssey system to quantify active enzymes involved in fertilization.
brad.stith@ucdenver.edu     303.315.7669
John Swallow photo

John Swallow

Ph.D. • Professor • Department Chair
Department of Integrative Biology
Expertise Areas: Experimental Comparative Physiology, Evolutionary Biology and Animal Behavior
john.swallow@ucdenver.edu     303.315.7610
Profile portrait of Diana Tomback.

Diana F. Tomback

Ph.D. • Professor
Department of Integrative Biology
Expertise Areas: The evolution, ecology, and population biology of bird-dispersed pines and their corvid dispersers; and, the conservation and restoration of five-needle white pines in western North America.
diana.tomback@ucdenver.edu     303.315.7642
Alan Vajda photo

Alan Vajda

Ph.D. • Associate Professor • Graduate Program Director
Department of Integrative Biology
Expertise Areas: Endocrine Disruption Environmental Toxicology Ecological Developmental Biology
alan.vajda@ucdenver.edu     303.315.7640
Mike Wunder photo

Mike Wunder

Ph.D. • Associate Professor
Department of Integrative Biology
Expertise Areas: I study animal population biology with a special interest in migratory systems. Migratory systems are useful models because conditions experienced at one place and time influence dynamics observed in distant locations; these are systems that link the biology and health of continents. My long-term goal is to understand factors regulating population demography and geographic range distributions, so that we can predict responses to disease epidemics and changes in climate, environmental health, and human land use. I combine fieldwork, lab work and modeling to study these systems and have developed novel statistical tools for determining dietary and geographic histories from chemical and molecular compositions of animal tissues.
michael.wunder@ucdenver.edu     303.315.7661