The POKY team, led by Prof. Woonghee Lee in the Chemistry department (right in photo), proudly announces the publication of their article “A-SIMA/A-MAP: A Comprehensive Toolkit for NMR-based Metabolomics Analysis” in the journal Metabolomics. This groundbreaking work introduces two innovative computational tools—A-SIMA (Advanced-Software for Interactive Metabolite Analysis) and A-MAP (A Multivariate Analysis Program)—designed to advance metabolomics research by streamlining metabolite identification and statistical analysis processes within the POKY suite.
Abigail Chiu, the first author of the paper (left in photo), spearheaded the development of A-SIMA and A-MAP as part of her master’s thesis. These tools showed her dedication to creating innovative computational solutions that are as user-friendly as they are powerful. Integrating these programs into the POKY platform led to a significant improvement in the accessibility of advanced metabolomics analysis for researchers worldwide. Abigail is now a 1st year PhD student in the Integrative and Systems Biology program.
These intuitive and sophisticated tools represent a major advance in NMR-based metabolomics research. A-SIMA and A-MAP have the potential to transform how researchers approach metabolite identification and statistical modeling by using resources that prioritize both functionality and ease of use.
Reference:
Chiu, A., Rahimi, M. & Lee, W. A-SIMA/A-MAP: a comprehensive toolkit for NMR-based metabolomics analysis. Metabolomics 21, 10 (2025). https://doi.org/10.1007/s11306-024-02208-w