Publications

Publications from the Knight lab: (student coauthors in italics)

  1. Chon, N.L., Tran, S., Miller, C.S., Lin, H., and Knight, J.D. (2023) A Conserved Electrostatic Membrane-Binding Surface in Synaptotagmin-Like Proteins Revealed Using Molecular Phylogenetic Analysis and Homology Modeling. BioRxIV: https://www.biorxiv.org/content/10.1101/2023.07.13.548768v1
  2. Anantharam, A., and Knight, J.D., eds. (2022) Exocytosis: From Molecules to Cells. London: Biophysical Society/IOP Press. https://iopscience.iop.org/book/edit/978-0-7503-3771-7
  3. Knight, J.D., Budd, S., Bruehl, M., and Pan, D. (2021) A Paired Set of Biochemistry Writing Assignments Combining Core Threshold Concepts, Information Literacy, and Real-World Applications. J Chem Educ 98, 3758-3766. https://doi.org/10.1021/acs.jchemed.1c00115  
  4. Pan, D., Budd, S., Bruehl, M., and Knight, J.D. (2021) Tracking Information Literacy in Science Students: A Longitudinal Case Study of Skill Retention from General Chemistry to Biochemistry. J Chem Educ 98, 3749-3757. https://doi.org/10.1021/acs.jchemed.1c00114
  5. Knight, J.D., Shearn, C.T., and Beauchamp-Pérez, C. (2021) A surprising modification lowers the lipid binding affinity of a membrane trafficking protein. ASBMB Today. https://www.asbmb.org/asbmb-today/science/082421/a-surprising-modification-lowers-the-lipid
  6. Alnaas, A.A., Watson-Siriboe, A., Tran, S., Negussie, M., Henderson, J.A., Osterberg, J.R., Chon, N.L., Harrott, B.M., Oviedo, J., Lyakhova, T., Michel, C., Reisdorph, N., Reisdorph, R., Shearn, C.T., Lin, H., and Knight, J.D. (2021) Multivalent lipid targeting by the calcium-independent C2A domain of synaptotagmin-like protein 4/granuphilin. J Biol Chem 296, 100159. https://doi.org/10.1074/jbc.RA120.014618
  7. Tran, H.T., Anderson, L.A., and Knight, J.D. (2019) Membrane Binding Cooperativity and Co-insertion by C2AB Tandem Domains of Synaptotagmins 1 and 7.  Biophysical Journal 116, 1025-1036.  doi: 10.1016/j.bpj.2019.01.035
  8. MacDougall, D.D., Lin, Z., Chon, N.L., Jackman S., Lin, H., Knight, J.D., and Anantharam, A.  (2018) The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis.  J. Gen. Physiol. 150 (6), 783-807.  http://jgp.rupress.org/content/150/6/783
  9. Schenk, N.A., Dahl, P.J., Hanna, M.G., Audhya, A., Tall, G.G., Knight, J.D., and Anantharam, A. (2018) A simple supported tubulated bilayer system for evaluating protein-mediated membrane remodeling. Chemistry and Physics of Lipids 215, 18-28.  doi: 10.1016/j.chemphyslip.2018.06.002
  10. Hamilton, D., Coffman, M., Knight, J.D., and Reed, S.M. (2017) Lipid-Coated Gold Nanoparticles and FRET Allow Sensitive Monitoring of Liposome Clustering Mediated by the Synaptotagmin-7 C2A Domain.  Langmuir 33, 9222-9230. http://pubs.acs.org/doi/10.1021/acs.langmuir.7b01397
  11. Osterberg, J.R., Chon, N.L., Boo, A., Maynard, F.A., Lin, H., and Knight, J.D.  (2015) Membrane Docking of the Synaptotagmin 7 C2A Domain: Electron Paramagnetic Resonance Measurements Show Contributions from Two Membrane Binding Loops.  Biochemistry 54, 5684-5695.  http://pubs.acs.org/doi/abs/10.1021/acs.biochem.5b00421
  12. Chon, N.L., Osterberg, J.R., Henderson, J., Khan, H.M., Reuter, N., Knight, J.D., and Lin, H. (2015) Membrane Docking of the Synaptotagmin 7 C2A Domain: Computation Reveals Interplay between Electrostatic and Hydrophobic Contributions.  Biochemistry 54, 5696-5711.  http://pubs.acs.org/doi/abs/10.1021/acs.biochem.5b00422
  13. Vasquez, J.K., Chantranuvatana, K., Giardina, D.T., Coffman, M.D., and Knight, J.D. (2014) Lateral diffusion of proteins on supported lipid bilayers: Additive friction of synaptotagmin 7 C2A-C2B tandem domains.  Biochemistry 53, 7904–7913.  http://pubs.acs.org/doi/abs/10.1021/bi5012223
  14. Lyakhova, T.A. and Knight, J.D. (2014) The C2 domains of granuphilin are high-affinity sensors for plasma membrane lipids. Chemistry and Physics of Lipids, 182, 29-37.  Invited submission for special issue on phosphoinositides.  http://www.sciencedirect.com/science/article/pii/S0009308413001370
  15. Brandt, D.S., Coffman, M., Falke, J.J., and Knight, J.D. (2012) Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: Mechanistic contrast between isoforms 1 and 7.  Biochemistry 51, 7654-64.  http://pubs.acs.org/doi/abs/10.1021/bi3007115